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Diabetes Care 45:27532786 Dormandy JA, Charbonnel B, Eckland DJA et al (2005) Secondary prevention of macrovascular events in patients with type 2 diabetes in the proactive study (PROspective pioglitAzone clinical trial in macrovascular events): a randomised controlled trial

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There were no significant changes in LDL ("bad") cholesterol, HDL ("good") cholesterol, triglycerides, aerobic capacity, bone density, or fasting blood sugar and insulin levels

Although more expensive and time-consuming, animal models and human studies are more suitable for evaluation [19]

No published trial has tested this combination specifically